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2013 Searle Scholars April 3, 2013: Chicago, Illinois - Fifteen researchers in the chemical and biological sciences have been named as the 2013 Searle Scholars. Each will be awarded $300,000 to support his or her work during the next three years. Since the program’s inception in 1980, five hundred and twelve (512) Searle Scholars have shared over $106,642,500 in grants. This year, 176 applications were considered from recently appointed assistant professors, nominated by 125 universities and research institutions. The final selection of scholars was based on recommendations made by the program’s Scientific Advisory Board consisting of 12 scientists distinguished for their research and leadership across a wide range of fields. In selecting the Scholars, the Scientific Advisory Board looked for scientists who have already demonstrated innovative research with the potential for making significant contributions to chemical and biological research over an extended period of time.

“The research programs of this year’s Scholars exemplify the most exciting frontiers of chemistry and the biomedical sciences,” said Scientific Director Doug Fambrough. “Two of the 2013 Scholars are devising new approaches in synthetic organic chemistry with exceptional promise for development of anti-cancer and anti-pathogen drugs. The research programs of other Scholars focus on a much deeper understanding of the structure of bacterial membranes and cell walls, the development of the heart, skin, and nervous system, regulatory mechanisms relevant to the loss of growth control in cancers, the mechanisms underlying diabetes, obesity, and infection, and aspects of plasticity, memory, and computational power in the brain. What exciting times in research science! It is a privilege to be able to kick-start careers of such visionary young scientists.”

The funds that support the awards come from trusts established under the wills of John G. and Frances C. Searle. Mr. Searle was President of G.D. Searle & Co., of Skokie, Illinois, a research-based pharmaceutical company. Mr. and Mrs. Searle expressed the wish that some of the proceeds of their estates be used for the support of research in medicine, chemistry, and the biological sciences.

In 1980, members of the Searle family acting as Consultants to the Trustees of the Trusts established under the wills of Mr. & Mrs. John G. Searle recommended the development of a program of support for young biomedical scientists. This idea evolved into the Searle Scholars Program which is funded through grants from the family trusts to the Chicago Community Trust and administered by Kinship Foundation in Chicago, Illinois.

A list of the 2013 Scholars, including the title of their research project and the name of the institution that will administer the award is below:

Trever Bivona
University of California, San Francisco
Discovery and Molecular Characterization of Rational Companion Cancer Targets

Jason Crawford
Yale University
An Evolutionary Chemical Leap from Invertebrate to Human Bacterial Pathogenesis

Danelle Devenport
Princeton University
Establishment of Long-Range Tissue Polarity in a Regenerative Epithelium

Guangbin Dong
University of Texas at Austin
Natural Product-Based Small-Molecule Libraries for Drug Discovery

Sophie Dumont
University of California, San Francisco
Mechanical Architecture of the Kinetochore-Microtubule Interface

Adam Frost
University of Utah School of Medicine
Toward Atomic Resolution of Membranes and Membrane-Associated Machines

Sunil Gandhi
University of California, Irvine
Reactivating Cortical Plasticity Using Inhibitory Neuron Transplantation

Ethan Garner
Harvard University
Building a Mechanistic Understanding of Bacterial Cell Wall Growth Using High-resolution Dynamic Imaging

Rana Gupta
U. of Texas Southwestern Medical Center
Defining Adipocyte Progenitors and their Developmental Origins

Christopher Harvey
Harvard Medical School
Plasticity of Neural Circuit Dynamics in the Mouse Cortex During Learning

Brenton Hoffman
Duke University
Developing Molecular-scale Systems Mechanobiology

Christian Metallo
University of California, San Diego
Tracing the Metabolic Link Between Hypoxia and Obesity

Mary Red-Horse
Stanford University
Molecular Regulators of Venous Reprogramming During Coronary Development

Bozhi Tian
The University of Chicago
Silicon-based Biomaterials for an Electrical Study of Single Neuron Dynamics

Eduardo Torres
University of Massachusetts Medical School
Role of Protein Turnover Pathways in Aneuploid Cells

2012 April 13, 2012: Chicago, Illinois - Fifteen researchers in the chemical and biological sciences have been named as the 2012 Searle Scholars. Each will be awarded $300,000 to support his or her work during the next three years.

Since the program's inception in 1980, 497 Searle Scholars have shared more than $102,142,500 in grants. This year, 186 applications were considered from recently appointed assistant professors, nominated by 125 universities and research institutions. The final selection of scholars was based on recommendations made by the program's Scientific Advisory Board consisting of 12 scientists distinguished for their research and leadership across a wide range of fields.

In selecting the Scholars, the Scientific Advisory Board looked for scientists who have already demonstrated innovative research with the potential for making significant contributions to chemical and biological research over an extended period of time.

"The new Searle Scholars have in common that they are bold enough to embark on high-risk projects that offer the promise of leading to major advances in the basic sciences and to a deeper understanding of such scourges as tuberculosis, inflammatory diseases, cancer, and atherosclerosis. It is with the highest possible enthusiasm that we welcome them into the community of Searle Scholars," said Scientific Director Doug Fambrough.

The funds that support the awards come from trusts established under the wills of John G. and Frances C. Searle. Mr. Searle was President of G.D. Searle & Co., of Skokie, Illinois, a research-based pharmaceutical company. Mr. and Mrs. Searle expressed the wish that some of the proceeds of their estates be used for the support of research in medicine, chemistry, and the biological sciences.

In 1980, members of the Searle family acting as Consultants to the Trustees of the Trusts established under the wills of Mr. & Mrs. John G. Searle recommended the development of a program of support for young biomedical scientists. This idea evolved into the Searle Scholars Program which is funded through grants from the family trusts to the Chicago Community Trust and administered by Kinship Foundation in Chicago, Illinois.

A list of the 2012 Scholars, including the titles of their research projects and the names of the institution that will administer the awards follows:

Emily P. Balskus
Harvard University
Synthetic Chemistry in the Presence of Living Systems

Jesse D. Bloom
Fred Hutchinson Cancer Research Center
The Antigenic Evolvability of Influenza Hemagglutinin

Clifford P. Brangwynne
Princeton University
Scaling Nucleolar Function for Cell Growth Control

Mark M. Churchland
Columbia University
A Dynamical Systems Approach to Fundamental Questions in Neuroscience

Elissa A. Hallem
University of California, Los Angeles
The Cellular and Molecular Basis of Carbon Dioxide Response in Nematodes

Daniel J. Kronauer
The Rockefeller University
Genes, Individuals, Societies: A Multi-layered Approach to the Study of Social Insects

Katja A. Lamia
The Scripps Research Institute
Integration of Mammalian Metabolism and Circadian Rhythms

Gaby Maimon
The Rockefeller University
From Sensation to Action in Drosphila

Cristopher M. Niell
University of Oregon
Neural Circuits and Computations Underlying Visual Processing in the Mouse Cortex

Daniel K. Nomura
University of California, Berkeley
Mapping Dysregulated Metabolic Pathways in Cancer and Inflammatory Diseases

Daniel M. Rosenbaum
University of Texas
Southwestern Medical Center, Dallas
Mechanisms of Integral Membrane Signaling Proteins Involved in Human Disease

Susumu Takahashi
University of Southern California
Single-molecule Magnetic Resonance Spectroscopy

David M. Tobin
Duke University
Developmental Pathways Mediating the Granuloma, the Central Structure of Tuberculosis

Miguel A. Zaratiegui-Biurrun
Rutgers, The State University of New Jersey
The Replication of Heterochromatin: Epigenetic Inheritance and Genome Stability

Feng Zhang
Massachusetts Institute of Technology
Reverse Engineering: the Epigenetic Substrates of Memory

CHICAGO, ILLINOIS: Fifteen individuals doing research in the chemical and biological sciences will each have $300,000 to support their research programs during the next three years. The fifteen have been named as the 2011 Searle Scholars. Over the past 30 years, 482 Searle Scholars have shared over $97,642,500 in grants made since the program began in 1981. This year, 180 applications were considered from recently appointed assistant professors, nominated by 126 universities and research institutions. The final selection of Scholars was based on recommendations made by a Scientific Advisory Board of twelve scientists distinguished for their research and leadership in fields of interest to the Searle Scholars Program.

In selecting the Scholars, the Board looked for scientists who have already demonstrated innovative research with the potential for making significant contributions to biological research over an extended period of time.

The funds that support the awards come from trusts established under the wills of John G. and Frances C. Searle. Mr. Searle was President of G.D. Searle & Co., of Skokie, Illinois, a research-based pharmaceutical company. Mr. and Mrs. Searle expressed the wish that some of the proceeds of their estates be used for the support of research in medicine, chemistry, and biological science.

In 1980, members of the Searle family, acting as Consultants to the Trustees of the Trusts established under the wills of Mr. & Mrs. John G. Searle, recommended the development of a program of support for young biomedical scientists. This idea evolved into the Searle Scholars Program, which is funded through grants from the family trusts to the Chicago Community Trust and administered by Kinship Foundation in Chicago, Illinois.

A list of the 2011 Scholars and the names of the institution that will administer the award follows:

Alexei A. Aravin
California Institute of Technology

Sandeep R. Datta
Harvard Medical School

Danica G. Fujimori
University of California, San Francisco

Wendy S. Garrett
Harvard School of Public Health

Richard E. Green
University of California, Santa Cruz

Nicholas T. Ingolia
Carnegie Institution of Washington

Megan C. King
Yale University, School of Medicine

Jared C. Lewis
University of Chicago

Attila Losonczy
Columbia University

Luciano A. Marraffini
Rockefeller University

Elizabeth M. Nolan
Massachusetts Institute of Technology

David J. Pagliarini
University of Wisconsin, Madison

Patrick Seale
University of Pennsylvania

Samuel Sidi
Mount Sinai School of Medicine

Joseph C. Sun
Memorial Sloan-Kettering Cancer Center

CHICAGO, ILLINOIS - Fifteen individuals doing research in the chemical and biological sciences will each have an additional $300,000 to support their research programs during the next three years. The fifteen have been named as the 2010 Searle Scholars. Over the past 29 years, 467 Searle Scholars have shared over $93,142,500 in grants, made since the program began in 1981. This year, 180 applications were considered from recently appointed assistant professors, nominated by 120 universities and research institutions. The final selection of Scholars was based on recommendations made by a Scientific Advisory Board of twelve scientists distinguished for their research and leadership in fields of interest to the Searle Scholars Program.

In selecting the Scholars, the Board looked for scientists who have already demonstrated innovative research with the potential for making significant contributions to biological research over an extended period of time.

The funds that support the awards come from trusts established under the wills of John G. and Frances C. Searle. Mr. Searle was President of G.D. Searle & Co., of Skokie, Illinois, a research-based pharmaceutical company. Mr. and Mrs. Searle expressed the wish that some of the proceeds of their estates be used for the support of research in medicine, chemistry, and biological science.

In 1980, members of the Searle family, acting as Consultants to the Trustees of the Trusts established under the wills of Mr. and Mrs. John G. Searle, recommended the development of a program of support for young biomedical scientists. This idea evolved into the Searle Scholars Program, which is funded through grants from the family trusts to the Chicago Community Trust and administered by Kinship Foundation in Northbrook, Illinois.

A list of the 2010 Scholars, including the names of the institution that will administer the award is listed below:

Theodor Agapie
California Institute of Technology

David Biron
University of Chicago

Sreekanth H. Chalasani
Salk Institute for Biological Studies

Heather R. Christofk
University of California, Los Angeles

Ila R. Fiete
University of Texas, Austin

Thomas Gregor
Princeton University

Katherine A. Henzler-Wildman
Washington University

Seth B. Herzon
Yale University

Bo Huang
University of California, San Francisco

Nelson C. Lau
Brandeis University

David Mclean
Northwestern University

Maxence V. Nachury
Stanford University

Ernest J. Petersson
University of Pennsylvania

Antonina I. Roll-Mecak
National Institute of Health

Emily R. Troemel
University of California, San Diego

Elaine Fuchs, along with eight other laureates, will be honored during a White House ceremony with President Obama on October 7. She is being honored "for her pioneering use of cell biology and molecular genetics in mice to understand the basis of inherited diseases in humans and her outstanding contributions to our understanding of the biology of skin and its disorders, including her notable investigations of adult skin stem cells, cancers and genetic syndromes."

CHICAGO, ILLINOIS - Fifteen individuals doing research in the chemical and biological sciences will each have an additional $300,000 to support their research programs during the next three years. The fifteen have been named as the 2009 Searle Scholars. CHICAGO, ILLINOIS - Fifteen individuals doing research in the chemical and biological sciences will each have an additional $300,000 to support their research programs during the next three years. The fifteen have been named as the 2009 Searle Scholars. Over the past 28 years, 452 Searle Scholars have shared over $88,640,000 in grants made since the program began in 1981. This year, 178 applications were considered from recently appointed assistant professors, nominated by 120 universities and research institutions. The final selection of Scholars was based on recommendations made by a Scientific Advisory Board of twelve scientists distinguished for their research and leadership in fields of interest to the Searle Scholars Program.

In selecting the Scholars, the Board looked for scientists who have already demonstrated innovative research with the potential for making significant contributions to biological research over an extended period of time.

The funds that support the awards come from trusts established under the wills of John G. and Frances C. Searle. Mr. Searle was President of G.D. Searle & Co., of Skokie, Illinois, a research-based pharmaceutical company. Mr. and Mrs. Searle expressed the wish that some of the proceeds of their estates be used for the support of research in medicine, chemistry, and biological science.

In 1980, members of the Searle family acting as Consultants to the Trustees of the Trusts established under the wills of Mr. & Mrs. John G. Searle, recommended the development of a program of support for young biomedical scientists. This idea evolved into the Searle Scholars Program, which is funded through grants from the family trusts to The Chicago Community Trust and administered by Kinship Foundation in Northbrook, Illinois.

A list of the 2009 Scholars and the names of the institution that will administer the awards can be found below.

Philip H. Bradley, Fred Hutchinson Cancer Research Center
Iain M. Cheeseman, Massachusetts Institute of Technology
Danica Chen, University of California, Berkeley
Mauro Costa-Mattioli, Baylor College of Medicine
Bianxiao Cui, Stanford University
Gregory S. Engel, University of Chicago
Nevan J. Krogan, University of California, San Francisco
Andreas Martin, University of California, Berkeley
Javier F. Medina, University of Pennsylvania
John Novembre, University of California, Los Angeles
Benjamin Ohlstein, Columbia University Medical Center
John L. Rinn, Harvard Medical School
Beth A. Shapiro, Pennsylvania State University
Doris Y. Tsao, California Institute of Technology
Weiwei Zhong, Rice University

Cedric Chernick, Director of the Searle Scholars Program from its founding in 1980 until 1995, passed away on Thursday, April 2. He played a pivotal role in the conception and organization of the Program, and he was greatly appreciated and admired by Scholars, Advisors, staff and the Searle family for his wisdom, impeccable judgment, great energy, and charming, gentle wit. Following his retirement, Cedric remained a source of sound advice and enthusiastic support. Services will be held on Sunday, April 5th at 2:00 pm at Congregation Rodfei Zedek, 5200 S. Hyde Park Blvd., Chicago. Interment will be in Oak Woods Cemetery. In lieu of flowers, memorials in his memory to should be directed to: Congregation Rodfei Zedek, 5200 S. Hyde Park Blvd, Chicago, IL 60615 or to: Museum of Science and Industry, 57th Street and Lake Shore Drive, Chicago, IL 60637.