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SEARLE SCHOLARS PROGRAM

Scholar Profile
  • George Barany
  • Professor
  • Department of Chemistry
  • University of Minnesota
  • 207 Pleasant Street SE
    Minneapolis, MN 55455-0431
  • Voice: 612/625-1028
  • Fax: 612/626-7541
  • E-mail: barany@umn.edu
  • Personal Homepage
  • 1982 Searle Scholar
Research Interests

Biological Chemistry

  • peptide synthesis, particularly the solid-phase method
  • protecting groups for organic functionalities, with an emphasis on the concept of "orthogonality"
  • chemistry of thiols, disulfides, and polysulfanes
  • sulfurization reagents for synthetic antisense DNA and RNA
  • functionalization of soluble and insoluble polymers
  • elucidation of labile structures by mass spectrometry
  • attack on problems of biological interest from a chemical angle
  • pharmaceutical effects of garlic and onion constituents
  • rational design of protein analogues with altered specificities
  • mechanism of protein folding
  • role of sugars, phosphates, and other posttranslational modifications for structure and function of peptide conjugates
  • preparation of DNA and PNA arrays for detection of genetic diseases
  • chemical combinatorial libraries

 

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