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SEARLE SCHOLARS PROGRAM

Scholar Profile
  • Edgar T. Walters

  • Director

  • Program in Cell and Regulatory Biology

  • Department of Integrative Biology and Pharmacology

  • University of Texas Medical School

  • P. O. Box 20708

  • Houston, TX 77225

  • E-mail: edgar.t.walters@uth.tmc.edu

  • Personal Homepage

  • 1984 Searle Scholar
Research Interests

Evolution of Memory Mechanisms

We use simple animals such as the marine snail Aplysia as models that permit detailed tests of hypotheses about the evolution of memory mechanisms from adaptive cellular reactions to injury. Knowing the neuronal circuitry involved in defensive behavior, we are examining alterations in individual neurons that contribute to aversive learning and memory, neural regeneration, and to the functional equivalent of "pain", hyperalgesia, and analgesia. Behavioral, neurophysiological (intracellular recording, voltage clamping, microinjection), pharmacological, morphological and molecular methods are used.
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