Differentiation of Neural Crest Cells
David Anderson's laboratory investigates how different types of neurons and glia
are generated from the neural crest, a uniquely vertebrate structure. The group
has isolated neural crest stem cells and progenitor cells, and has immortalized
them to produce continuous cell lines. Anderson's group has also isolated
vertebrate homologues of Drosophila genes that control neuronal determination,
and is examining their function by gene knockout experiments in mice.
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