Cell Cycle Regulation

• The control of progression through the cell cycle using cell-free extracts of Xenopus eggs.
• The molecular basis for nuclear envelope assembly and its regulation using cell-free extracts of Xenopus eggs.

RESEARCH IN PROGRESS

• Characterization of the destruction pathway for mitotic cyclins during the transition from mitosis to G1-phase of the cell cycle.
• Isolation and characterization of precursors on the nuclear envelope.
• The behavior of the nuclear pore protein p62 during nuclear envelope assembly and disassembly.