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SEARLE SCHOLARS PROGRAM

Scholar Profile
             
  • Alexandra C. Newton
  • Professor
  • Department of Pharmacology
  • University of California, San Diego
  • 9500 Gilman Drive
    La Jolla, CA 92093-0640
  • Voice: 858.534.4527
  • Fax: 858.534.6020
  • E-mail: anewton@ucsd.edu
  • Personal Homepage
  • 1989 Searle Scholar
Research Interests

Our lab investigates the biology and chemistry of protein kinase C and its upstream kinase, the phosphoinositide-dependent kinase, PDK-1. We are interested in the coordinated regulation of both these enzymes in cellular signalling. Current projects focus on the molecular mechanisms governing the regulation of these key signalling kinases by:

  • lipid interactions
  • regulatory and targeting proteins
  • phosphorylation
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