Alexandra C. Newton

Current Institution
University of California, San Diego
Department of Pharmacology

Scholar: 1989

Awarded Institution
Indiana University


Research Interests

Our lab investigates the biology and chemistry of protein kinase C and its upstream kinase, the phosphoinositide-dependent kinase, PDK-1. We are interested in the coordinated regulation of both these enzymes in cellular signalling. Current projects focus on the molecular mechanisms governing the regulation of these key signalling kinases by:

  • lipid interactions
  • regulatory and targeting proteins
  • phosphorylation