Bo Huang
Research Interests
Cellular processes are often carried out by coordinated participation of many proteins. To understand how them work together, we are developing super-resolution microscopy and single-molecule imaging methods and using them to study the following problems: ,
(1) proteins organization in large complexes such as the nuclear pore complex and centrosome, ,
(2) dynamic protein interaction in regulating G-protein coupled receptor signaling, ,
(3) cell adhesion molecules in controlling the development of the nervous system, and,,
(4) protein-DNA interactions in the nucleus. ,
We are also interested in combining synthetic chemistry, protein engineering and microfluidics-based high-throughput screening to create new fluorescent probes that allow us to better study these cellular structures and processes.,