Neil Kelleher

Current Institution
Northwestern University
Department of Chemistry and <br/>Department of Molecular Biosciences

Scholar: 2000

Awarded Institution
University of Illinois at Urbana Champaign


Research Interests

Professor Kelleher is a bioanalytical chemist and is interested in finding novel posttranslational modifications and studying enzymatic mechanisms of large enzymes (>500 kDa). Using high-resolution mass spectrometry to spearhead the research, we correlate protein fragmentation data to fully sequenced genomes to scan for chemically-altered gene products and the cellular alteration machinery. Also, the biosynthesis of many clinically-used drugs occurs on ultralarge enzymes acting as solid supports for covalent catalysis, ideal for study by mass spectrometry.